Senior Biostatistician (Bayesian Adaptive Clinical Trials)

Senior Biostatistician (Bayesian Adaptive Clinical Trials)

A Senior Biostatistician is sought for the design and analysis of clinical trials (RTCs) for a variety of clients on an ongoing contractual basis with view to a full time role. This role requires expertise in Bayesian simulation, modelling and adaptive trials methodology.

This is a remote part-time role.

Please note the hourly rate (negotiable) is displayed in USD but will be paid in GBP or as preferred.

Responsibilities:

· Lead and manage the study design and statistical analysis for multiple simultaneous clinical trials.

· Responsible for all statistical aspects including sample size calculation, study design, SAP, SAR, SSR, statistical analysis, Biostatistics QC.

. Data visualisation, results write-up and reporting to publication standard, presentation of findings in ppt format.

· Collaborating with Statistical programmer to produce SDTM and ADaM data sets.

· Author and/or review Statistical Analysis Plans (SAPs) centred around the study protocols.

· Perform initial Bayesian meta-analyses to aid the preliminary design.

· Perform interim analyses and updates as required

Requirements:

· Coursework MSc in BIOSTATISTICS and/or PhD in biostatistics

· Expertise in SAS, R and Stata

· 5+ years relevant experience within the pharma or medtech industry.

· Comprehensive knowledge of advanced Bayesian methodology for a clinical trials context.

· Experience with umbrella, basket and platform trial designs.

· Expertise in Bayesian techniques such as Bayesian meta-analysis, Bayesian Adaptive designs and inherent interim analyses is essential.

· Practical knowledge of all relevant clinical research regulatory guidance and standards (e.g. ICH and EMA).

· High level of communication skills over different modalities such as email, phone and video-link.

Experience in a specific area of clinical trials (such as oncology, neurology etc) or industry (such as pharma/medical devices/biotechnology) highly regarded.

A cover letter should address each of the above requirements.\

Please apply on the Lifelancer platform at the below link for screening steps & quicker response.

https://lifelancer.com/jobs/view/72e5563073e8bb77a5dc67f076233c67