Job Openings Principal Machine Learning Engineer

About the job Principal Machine Learning Engineer

Job Title: Principal Machine Learning Engineer

Job Location: Hyderabad, Telangana, India

Job Location Type: On Site

Job Contract Type: Full time

Job Seniority Level:

The AI/ML Lead will head Amgen’s AI/ML practice within the Innovation Lab, driving the development, validation, and deployment of machine learning and GenAI solutions across R&D, Manufacturing, and Commercial domains.

This role requires strong technical depth, leadership skills, and a deep understanding of responsible AI frameworks within regulated environments.
 

Key Responsibilities

  • Lead AI/ML strategy and implementation across multiple PoDs in the Innovation Lab.
  • Translate Amgen’s business objectives into data-driven AI/ML initiatives.
  • Define architecture, standards, and best practices for model design, training, and validation.
  • Oversee MLOps and CI/CD integration to enable scalable model deployment.
  • Guide the team on data preparation, feature engineering, and experimentation.
  • Review and approve model validation reports, metrics, and explainability artifacts.
  • Ensure compliance with Responsible AI, GxP, and privacy frameworks.
  • Collaborate with SMEs and Data Governance leads to align models with business and ethical objectives.
  • Mentor engineers, fostering innovation and technical excellence.

Required Qualifications

  • 10–15 years of experience in data science or machine learning engineering.
  • Proven leadership in AI/ML project delivery and technical governance.
  • Expertise in Python, TensorFlow, PyTorch, Scikit-learn, or similar ML frameworks.
  • Experience with MLOps, MLflow, Databricks, and AWS SageMaker.
  • Strong grounding in model lifecycle management and validation documentation.
  • Excellent analytical, communication, and cross-functional collaboration skills.

Preferred Skills

  • Experience with GenAI / LLM architectures (LangChain, OpenAI APIs, Hugging Face).
  • Prior exposure to pharma, biotech, or life sciences R&D.
  • Certification in Machine Learning / Data Science / AWS AI Specialist.
  • Familiarity with data privacy regulations (HIPAA, GDPR) and ethical AI standards.
     



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