Senior Director/Vice President, Medical Affairs

About us:

Braveheart Bio is a Bay Area–based biopharmaceutical company pioneering best-in-class therapies for cardiovascular disease. Our lead program is a next-generation myosin inhibitor, licensed from Hengrui Pharma, being developed to transform the treatment of hypertrophic cardiomyopathy (HCM)—the most common inherited cardiac disease.

Currently in Phase 3 clinical development in China for the more common obstructive form of HCM, our candidate has demonstrated a compelling clinical profile that may position it as a best-in-class therapy with meaningful differentiation.

With a proven leadership team, a strong financial foundation, and a high-value late-stage asset, Braveheart Bio represents an outstanding opportunity for ambitious, mission-driven professionals to make a tangible impact in a high-profile and rapidly evolving therapeutic area.

The role:

The Senior Director/Vice President of Medical Affairs will serve as Braveheart’s senior medical leader and a key architect of the medical strategy supporting the global development and future launch of BHB-1893 for hypertrophic cardiomyopathy (HCM). This individual will shape and execute a comprehensive medical affairs roadmap spanning late-stage development, launch readiness, and lifecycle planning. A core responsibility of this role is building trusted scientific partnerships with the global HCM community—including key opinion leaders, investigators, and patient advocacy groups—to strengthen external engagement and support meaningful scientific exchange. This individual will also provide leadership and oversight for all medical activities to ensure they reflect the highest standards of scientific integrity and remain fully compliant with regulatory and industry guidelines. As Braveheart grows, the Senior Director/VP of Medical Affairs will build and lead the medical affairs function, establishing the people, processes, and systems needed to support Phase 3 execution, data generation, launch planning, and post-approval medical excellence.

Key responsibilities:

• Develop and drive the global medical affairs strategy and tactical plan for BHB-1893 in alignment with Braveheart’s overall development and commercial objectives
• Build and lead a high-performing medical affairs organization, including medical communications, medical information, publications, and field medical capabilities
• Cultivate strong relationships with key external stakeholders such as clinicians, scientific leaders, advocacy groups, payers, and regulatory bodies
• Provide medical governance and ensure all external-facing medical activities and materials comply with applicable laws, regulations, and industry standards
• Oversee development and delivery of scientific training, medical education, and medical information resources
• Lead the publication and scientific communication strategy to support data dissemination and evidence transparency
• Contribute medical insight into protocol development, evidence generation planning, and interpretation of clinical data
• Represent Braveheart at scientific congresses, advocacy meetings, and key partnership discussions
• Serve as a medical strategic partner to the Commercial team, providing clinical insight for content development, messaging, and launch readiness activities
• Maintain deep awareness of the scientific and competitive landscape to inform strategy and position BHB-1893 effectively

Required experience & skills:

• MD preferred; PhD or PharmD in a relevant scientific discipline may also be considered
• Clinical background in cardiovascular medicine, ideally including HCM or heart failure experience
• At least 5 years of medical affairs experience in biotechnology or pharmaceuticals, ideally supporting competitive brands or complex specialty products
• Strong clinical and scientific judgment, with the ability to translate data into actionable medical and strategic insights
• Demonstrated success building and leading teams in a matrixed, cross-functional environment
• Excellent communication and interpersonal skills with the ability to engage credibly with internal and external stakeholders
• Ability to work independently and collaboratively in a fast-moving, resource-lean environment
• Proven ability to manage multiple priorities and deliver high-quality outputs under tight timelines
• Commitment to excellence, continuous learning, adaptability, and proactive problem-solving
• Strong written and verbal communication skills with a collaborative, team-oriented approach
• Ability to thrive in a fast-paced, dynamic environment and remain comfortable with change and ambiguity
• Flexible, proactive, and hands-on mindset with a roll-up-your-sleeves, can-do attitude

We are an equal opportunity employer.

We are committed to inclusion and diversity, and we do not discriminate on the basis of race, gender, religion, gender, sexual orientation, age, color, marital status, veteran status, disability status, national origin, or any characteristic protected under applicable law.