Senior Chemist

Join Pharmacosmos in a newly established role, where you will be at the forefront of API process development, leading and coordinating key activities from early design through to scale-up and technology transfer.

Assume responsibility in advancing chemical and pharmaceutical development both internally and with CDMO Partners
As Senior Chemist, you will report directly to the Senior Director, Head of Chemical and Pharmaceutical Development and become part of the CMC department. Across Pharmacosmos Carbohydrate and Iron Complex Manufacturing, you will be responsible for the development of new carbohydrate-based products and leading and coordinating key activities from conception, through to full scale production and commercialization. You will serve as the primary liaison for synthetic API development projects, leading cross-functional efforts between internal R&D teams and external Contract Development and Manufacturing Organizations (CDMOs). Furthermore, you will make chemical characterizations of products and ensure process development and innovation in synthetic APIs, applying Quality by Design (QbD) and Design of Experiments (DoE) methodologies to ensure robust, scalable, and cost-effective processes. Moreover, you will support CMC related development projects for pharmaceutical projects in the pipeline, as well as identify root causes and/or optimize existing processes and products. Conduct risk assessments and implement process improvements. Additionally, contributing to chemistry and CMC sections in regulatory filing documents, i.e., writing and proofreading of documents for regulatory drug applications (e.g., Drug Master Files) and taking part in the preparation of answers to authorities as well as regulatory submissions such as Investigational Medicinal Product Dossiers (IMPDs), Investigational New Drug (IND) applications, and Chemistry, Manufacturing, and Controls (CMC) sections. Moreover, you will to some extent engage in limited hands-on laboratory work (approximately one day per week) to support process development, troubleshoot critical experiments, and validate key findings. Finally, you will collaborate with Quality Assurance (QA), Regulatory Affairs, Analytical, Manufacturing teams, CDMOs to align and support the development efforts with overall business strategies.

Highly skilled chemist with drug substance experience
You are expected to hold a MSc or PhD degree in Chemistry (either Synthetic Organic/Inorganic Chemistry, Medicinal Chemistry, or Chemical Engineering) or similar, combined with significant experience (7 - 10 years) in CMC, including extensive experience with drug substance development. Your professional journey boasts proven, solid experience in a highly specialized scientific setting within the pharmaceutical industry. Your style of work is underscored by exceptional communication, project management skills, and the ability to thrive in dynamic, fast-paced environments. With a demonstrated track record of success, you bring valuable hands-on industry experience, including collaborations with CDMOs and regulatory documentation. You have proven experience applying QbD and DoE principles, as well as managing complex projects, securing overall project objectives.

Personally, you are structured, proactive, responsible, and result-oriented with an empathic and respectful mindset. You have strong analytical capabilities paired with excellent problem-solving skills. You are self-driven with an eagerness to innovate and to conceive, plan, and execute API process development. As a member of a highly dedicated team that thrives on collaboration, it is essential that you demonstrate excellent planning, coordination, and prioritization skills, and that you can work independently as well as in a collaborative environment. This will also become important when communicating with key stakeholders to assist with decision-making, and when discussing technical issues at the plant staff level as well as with groups of technical peers. Your robust ethical foundation fosters a profound dedication to integrity and an unwavering commitment to quality in all of your work, empowering you to effectively navigate through ambiguity and change. Finally, you are fluent in English, both written and verbal.

Impact the future development of iron- and carbohydrate-based treatments
This is your chance to embark upon a personal and organizational journey in a dynamic company where your know-how is greatly needed for the future development of Pharmacosmos. The recruitment process is carried out by Venaris Executive Search. For more information regarding the position, please reach out to Sr. Executive Search Consultant, Lars Nordlund, on +45 3123 3018. All requests will be handled confidentially. If this position is for you, do not hesitate to apply by uploading your CV - it is not necessary to include a cover letter.

Pharmacosmos
Founded in 1965, Pharmacosmos is a global healthcare pioneer in carbohydrate chemistry and a leader in the development of innovative treatments for blood diseases, including iron deficiency anemia and cryopreservation technology. On September 18th, 2024, Pharmacosmos announced the successful completion of their acquisition of G1 Therapeutics, a commercial-stage oncology company. The acquisition aligns perfectly with Pharmacosmos' strategy by leveraging their extensive expertise in blood diseases, positioning the company for its next phase of growth and strengthening its global commercial portfolio. Headquartered in Holbæk, Denmark, Pharmacosmos employs 650 dedicated employees, with products marketed in over 40 countries worldwide. Please also visit www.pharmacosmos.com.